Roland Garros champion Coco Gauff arrives as one of the main contenders, but she has never progressed beyond the fourth round in London.
Last year’s runner-up Jasmine Paolini, the Italian world number four, will look to go one step better this year.
Meanwhile, former world number one Iga Swiatek – who beat Paolini handily in Bad Homburg on Friday – and 2022 Wimbledon champion Elena Rybakina will also hope to challenge.
British number one Emma Raducanu leads home hopes in the women’s draw, where she is joined by Katie Boulter and Sonay Kartal, who have both spent time in the world’s top 50 of late.
However, Raducanu has been handed a difficult draw. Former champion Marketa Vondrousova is a possible second-round opponent, while Sabalenka is likely to be waiting should she reach round three.