While Boulter, Fearnley, Raducanu and Xu start their tournaments on the main show courts, there will be 10 other Britons in action around the grounds, with play beginning at 11:00 BST.
Cameron Norrie, a semi-finalist three years ago, plays second on court 18 as he faces a tricky opponent in Spain’s Roberto Bautista Agut.
Sonay Kartal features in the court three opener against Latvian 20th seed and former French Open winner Jelena Ostapenko.
The final two matches on court 17 feature British interest as Harriet Dart takes on Hungarian Dalma Galfi before world number 796 Mika Stojsavljevic faces American 31st seed Ashlyn Krueger.
Stojsavljevic, 16, is a wildcard entry and won last year’s US Open girls’ title.
Her fellow British 16-year-old Hannah Klugman is third on court 12 against Canada’s Leylah Fernandez – the player Raducanu beat in the 2021 US Open final. Klugman, who was brought up in Wimbledon Village, reached the girls’ final at the French Open in June.
British world number 719 Oliver Tarvet makes his Wimbledon debut against Swiss Leandro Riedi in the opening match on court four. Having come through qualifying, Tarvet is in the unfortunate position of not being able to claim all the prize money he would be due because of rules implemented in the US collegiate system.
The fourth match on court four features Henry Searle – Britain’s 2023 boys’ Wimbledon champion – playing American Ethan Quinn.
British world number 465 Arthur Fery takes on Australian 20th seed Alexei Popyrin, on Court 15 – followed by Billy Harris’ match with Serbian Dusan Lajovic.
Oliver Crawford, who was born in the US to British parents, makes his Grand Slam debut at the age of 26 against Italian Mattia Bellucci on court 16.